What is Mounjaro?

Mounjaro is an innovative prescription medicine used to treat type 2 diabetes by helping lower blood sugar levels. In addition to improving glycemic control, Mounjaro weight loss benefits have also been proven in clinical trials when combined with diet and exercise. It is a once-weekly injection that can be self-administered, working best alongside healthy lifestyle changes.

How Does Mounjaro Work?

The active ingredient in Mounjaro, tirzepatide, targets two gut hormone receptors — GIP and GLP-1. By stimulating insulin release when glucose levels are high, reducing liver glucagon production, and slowing stomach emptying, it helps control post-meal sugar spikes. At the same time, it increases satiety, helping reduce appetite and calorie intake. This dual action explains how Mounjaro works for both diabetes management and weight loss.

Benefits of Mounjaro in Clinical Studies

Clinical trials involving over 6,000 adults with type 2 diabetes have shown significant improvements:

• Reduction in HbA1c by up to 2.6% depending on the study.

• Effective in combination with metformin, SGLT2 inhibitors, and insulin therapies.

• In weight management studies, patients using Mounjaro for weight loss achieved up to 15% body weight reduction on average, compared to 3% with placebo.

Over 85% of participants taking Mounjaro lost at least 5% of their body weight, highlighting its potential beyond blood sugar control.

Possible Mounjaro Side Effects

Like other prescription medicines, Mounjaro side effects may occur. The most common include nausea, abdominal pain, diarrhea, and decreased appetite. Rare but serious side effects such as thyroid cancer or pancreatitis have been reported. Patients should consult a healthcare provider before use and report any unusual symptoms.

Mounjaro Dosage Forms & Strengths

Mounjaro is available as a once-weekly subcutaneous injection in prefilled pens or single-dose vials. Strengths include:

• 2.5 mg, 5 mg, 7.5 mg, 10 mg, 12.5 mg, and 15 mg (0.5 mL solution).

Typical dosing schedule:

• Start with 2.5 mg once weekly for 4 weeks.

• Increase to 5 mg once weekly.

• If additional glucose control is needed, increase by 2.5 mg every 4 weeks.

• Maximum recommended dose: 15 mg once weekly.

⚠️ Note: The 2.5 mg starting dose is for treatment initiation and is not effective for glycemic control.