Dopamine hydrochloride injection concentrate, an inotrope and vasopressor for cardiogenic and distributive shock, is a WHO Essential Medicines List injection now supplied only as licensed generic, the originator brand Intropin having been discontinued.
M Care Exports supplies dopamine hydrochloride injection concentrate, an inotrope and vasopressor infused in intensive care to correct hypotension from cardiogenic or distributive shock. The originator brand, Intropin, is discontinued worldwide; every buyer today is sourcing licensed generic dopamine concentrate. M Care is a merchant exporter: we source FDA, MHRA and EU-registered generic dopamine lines through licensed Indian manufacturing and distribution channels and dispatch on quote, not from our own manufacturing.
Dopamine exporter and bulk supplier from India.
For hospital ICU pharmacy, ambulance-service and tender-desk orders, M Care quotes dopamine hydrochloride concentrate against buyer specification: vial size (5 mL or 10 mL), destination-country labelling language and batch documentation, drawn from licensed WHO-GMP manufacturer lines on the M Care roster. Because dopamine is dosed and titrated in micrograms per kilogram per minute on an infusion pump rather than as a fixed dose, and several ICU inotropes have run intermittently short in regulated markets in recent years, we confirm the buyer's required vial count and delivery window early and align CTD/eCTD or country-specific dossier paperwork to the destination regulator's requirements before dispatch.
Source
WHO-GMP-certified Indian manufacturing line, named on every quote.
Minimum order
No blanket MOQ. Set by the source manufacturer's minimum batch-release quantity for the strength and pack ordered.
Pricing
On request. Indicative FOB or CIF quote, formal proforma on confirmation.
Incoterms
EXW, FOB, CIF, CIP or DAP.
Payment
Letter of credit (sight or usance) and telegraphic transfer.
Documentation
WHO-GMP certificate of the source line, product-specific CoPP, batch CoA, method of analysis, Free Sale Certificate, Certificate of Origin, CTD or eCTD dossier. On request.
Shelf-life
Minimum remaining shelf-life agreed per order and confirmed on the proforma.
Response
Availability and CoPP status within two working days; pre-alert documents before dispatch.
Catecholamine inotrope and vasopressor, sourced and documented for export.
Dopamine hydrochloride is an endogenous catecholamine and inotrope that acts on dopaminergic, beta-1 and alpha-1 adrenergic receptors in a dose-dependent way, increasing cardiac contractility and, at higher infusion rates, causing vasoconstriction to raise blood pressure. It is given only as a continuous intravenous infusion, always diluted before administration and never as a bolus. The FDA label's flagship indication is to improve haemodynamic status in distributive shock or shock due to reduced cardiac output; the UK SmPC describes the same use as correction of haemodynamic imbalance in low-perfusion states linked to myocardial infarction, trauma, septicaemia, cardiac failure or open-heart surgery. Dopamine hydrochloride injection concentrate is supplied as 40 mg/mL, packed as 200 mg per 5 mL and 400 mg per 10 mL single-dose vials, requiring dilution in compatible intravenous fluids before use.
Active ingredient
Dopamine hydrochloride. Catecholamine inotrope and vasopressor.
Forms and strengths
200 mg/5mL (40mg/mL) concentrate for infusion vial; 400 mg/10mL (40mg/mL) concentrate for infusion vial.
Indications
Dopamine hydrochloride, an endogenous catecholamine inotrope and vasopressor indicated to improve haemodynamic status in cardiogenic and distributive shock. The originator brand Intropin is discontinued; supplied as licensed generic concentrate from Indian WHO-GMP facilities to regulated and semi-regulated markets outside India.
Administration
Intravenous. Concentrate for solution for infusion (injection).
Documentation
Batch-specific CoA, CoPP, manufacturing-site WHO-GMP certificate and stability data compiled per consignment, in the format the destination regulator expects.
Hospital pharmacies, licensed importers and tender desks across our export markets.
India is our origin. We do not sell into the Indian market.
Buyers for dopamine are mainly hospital ICU and critical-care pharmacies stocking inotropes and vasopressors for shock protocols, ambulance and emergency-medicine services, national and regional MoH tender desks running critical-care and anaesthesia formulary lists, licensed pharmaceutical wholesalers and importers, and NGO or hospital-support procurement programmes supplying critical-care units in markets where local registration is in place.
GCC registration routes
Supply against MoH registration held by your local licensed importer, or via the GCC central registration pathway.
UK unlicensed routes
Where no UK licence exists, the MHRA Specials and named-patient import routes cover clinically justified demand.
Tender desks
Bid-pack documentation assembled to the tender's specification, from CoPP to batch records.
Dossier support
CTD documentation from the sourcing manufacturer, compiled for your regulator's format.
What the dispensing pharmacist checks on dopamine.
Dopamine is titrated, not fixed-dosed: infusion typically starts at 2 to 5 mcg/kg/min for renal and cardiac effect, with increments up to 5 to 10 mcg/kg/min stepwise and an upper ceiling around 50 mcg/kg/min, so pump-ready concentrate and accurate weight-based calculation matter more than pack strength. It must always be diluted before infusion, given through a large vein or, ideally, a central line via infusion pump, and never as a bolus; abrupt discontinuation risks marked hypotension, so tapering is standard practice. Extravasation causes tissue ischaemia and, left untreated, necrosis: the FDA label specifies infiltrating the affected area with 5 to 10 mg phentolamine mesylate in 10 to 15 mL saline as soon as possible, ideally within 12 hours. Hypovolaemia should be corrected before starting dopamine, since it does not substitute for volume replacement. Some formulations contain sodium metabisulfite, which can trigger anaphylactic or asthmatic reactions in sulfite-sensitive patients, so this should be checked against the destination pack's excipient statement. No cold-chain handling is required; storage is at controlled room temperature.
The documentation pack a regulator actually asks for.
Dopamine hydrochloride injection concentrate is an ambient-temperature product, not a cold-chain line: what buyers need is batch-level certificate of analysis, CDSCO export documentation and, where the destination market requires it, CTD or eCTD-format dossier support so the buyer's own regulator can register the product. Dopamine hydrochloride is on the WHO Model List of Essential Medicines, in the section for medicines used in heart failure at the 40 mg/mL, 5 mL vial strength, which underlines its standing as a core critical-care agent rather than a niche inotrope. It is not a controlled drug. The originator brand, Intropin, has been discontinued; every dopamine injection now on FDA, MHRA and EU registers is a licensed generic, so buyers are not choosing between brand and generic here, only between generic manufacturers on documentation, batch reliability and price. Dopamine and related ICU inotropes have seen intermittent manufacturer-level supply constraints in regulated markets in recent years, which is one reason MoH and hospital tender desks increasingly qualify a second or third dopamine source rather than single-sourcing; M Care treats confirmed lead time and vial-count availability as a standing check before quoting, not a one-off step.
Buyers new to sourcing from India usually read the licensed import route explainer first, then the product page.
CoA and MoA, per batch
Batch-specific certificate and method of analysis from the sourcing manufacturer's QC release.
CoPP, WHO-GMP, MFG licence
Certificate of pharmaceutical product and site GMP certification issued via CDSCO channels, naming the actual manufacturing site.
CTD Module 3
Chemistry, manufacturing and controls documentation available from the sourcing manufacturer for registration filings.
Pack insert, labels, artwork
Destination-language patient information and labelling to the local regulator's standard, locked before shipment.
Pharmacovigilance
A named PV contact arranged in the destination market where the registration requires one.
Adjacent lines procurement desks order alongside dopamine.
Molecule · strength · volume · destination. One working day to a quote.
- Send us the specifics. Form and strength, pack preference, destination market and indicative volume for dopamine.
- We route to the right line. The enquiry goes to the WHO-GMP certified manufacturing partner whose certificates fit your regulator.
- Commercial and regulatory offer. FOB or CIF price with the documentation list, named manufacturing site and current certificate validity.
- Order, produce, release, ship. QC release on the Indian side, batch documents compiled, despatch on the agreed incoterm.
- After delivery. Batch records and certificates archived and retrievable for the life of the product on your shelf.
Dopamine supply, the specific questions.
Is Intropin still available, or only generic dopamine?
Intropin, the original branded dopamine injection, has been discontinued. Every dopamine hydrochloride injection concentrate on the market today, in the US, UK, EU and elsewhere, is a licensed generic. M Care sources FDA, MHRA and EU-registered generic dopamine concentrate through licensed Indian manufacturing and distribution channels; there is no branded version to compare it against.
What strengths and pack sizes does M Care supply?
Dopamine hydrochloride injection concentrate at 40 mg/mL, packed as 200 mg per 5 mL and 400 mg per 10 mL single-dose vials, matching standard ICU pump-dilution practice. Tell us your required vial size and count and we quote against current manufacturer availability.
Does dopamine need cold-chain shipping?
No. Dopamine hydrochloride injection concentrate is stored at controlled room temperature, 20 to 25 degrees Celsius, and travels on standard ambient-temperature logistics rather than the cold-chain lanes M Care validates for biologics and insulins. It still needs protection from excessive heat and light in transit, which our standard temperature-monitoring pack covers.
Is dopamine on the WHO Essential Medicines List?
Yes. Dopamine hydrochloride injection, 40 mg/mL in a 5 mL vial, appears on the WHO Model List of Essential Medicines in the section for medicines used in heart failure. That standing is one reason MoH tender desks across our export markets list it as a required critical-care stock item.
How is dopamine dosed, and does that affect what we should order?
Dopamine is given only as a continuous intravenous infusion, titrated by body weight from around 2 to 5 mcg/kg/min upward, never as a bolus. Because dosing scales with patient weight and clinical response rather than a fixed amount, ICU pharmacies typically hold stock against expected patient throughput rather than per-patient courses; tell us your unit's typical monthly vial usage and we size the order accordingly.
What happens if dopamine extravasates during infusion?
Extravasation risks tissue ischaemia and, if untreated, necrosis. The FDA label specifies infiltrating the affected area with 5 to 10 mg phentolamine mesylate in 10 to 15 mL of saline as soon as possible, within 12 hours of the event. This is a clinical-management step for the treating team; M Care's role is ensuring the product itself, and its labelling, reaches the pharmacy with the manufacturer's current prescribing information attached.
Who stands behind this page, and where its statements come from.
Reviewed by Dr. Rajat Bhatt, PharmD, Managing Director, M Care Exports. Last reviewed 2026-09-25.
This page is sourcing information for licensed importers, hospital procurement and tender desks. It is not medical, pharmaceutical or prescribing advice, and it is not a substitute for the approved product information of the line on your order. See our full disclaimer.
Send the specifics. You'll have a price inside one working day.
Form and strength, destination market and indicative volume. The Mumbai desk replies within one working day, including when the honest answer is that the route is not viable yet.