Cancidas (caspofungin), the echinocandin antifungal for invasive candidiasis and aspergillosis unresponsive to other therapy, is available as the originator brand and as generic caspofungin acetate for hospital and tender supply.
M Care Exports supplies Cancidas (caspofungin), originated by Merck and marketed by Merck Sharp & Dohme outside the US, alongside generic caspofungin acetate for injection. It is an echinocandin antifungal given by intravenous infusion for invasive candidiasis, aspergillosis refractory to or intolerant of other antifungal therapy, and empirical therapy in febrile neutropenic patients. M Care is a merchant exporter: we source Cancidas and generic caspofungin through licensed Indian distribution and manufacturing channels and dispatch on quote, not from our own manufacturing.
Caspofungin exporter and bulk supplier from India.
For hospital pharmacy, ICU and tender-desk orders, M Care quotes caspofungin against buyer specification: brand (Cancidas) or generic, 50mg and 70mg vial mix, and destination-market regulatory documentation, drawn from licensed WHO-GMP manufacturer lines on the M Care roster. Because caspofungin needs an unbroken refrigerated cold chain from origin to reconstitution, and its dose changes with hepatic impairment and with concomitant rifampicin, ciclosporin or tacrolimus, we confirm the buyer's cold-chain capability and concomitant-medication profile before dispatch, then align CTD/eCTD or country-specific dossier paperwork to the destination regulator's requirements.
Source
WHO-GMP-certified Indian manufacturing line, named on every quote.
Minimum order
No blanket MOQ. Set by the source manufacturer's minimum batch-release quantity for the strength and pack ordered.
Pricing
On request. Indicative FOB or CIF quote, formal proforma on confirmation.
Incoterms
EXW, FOB, CIF, CIP or DAP.
Payment
Letter of credit (sight or usance) and telegraphic transfer.
Documentation
WHO-GMP certificate of the source line, product-specific CoPP, batch CoA, method of analysis, Free Sale Certificate, Certificate of Origin, CTD or eCTD dossier. On request.
Shelf-life
Minimum remaining shelf-life agreed per order and confirmed on the proforma.
Response
Availability and CoPP status within two working days; pre-alert documents before dispatch.
Echinocandin antifungal (1,3-beta-D-glucan synthase inhibitor), sourced and documented for export.
Caspofungin is an echinocandin antifungal that inhibits 1,3-beta-D-glucan synthase, the enzyme fungal cells use to build their cell wall, an action mammalian cells do not share. It is given only by intravenous infusion over roughly one hour, never as an oral dose or an IV bolus. The SmPC's licensed indications are invasive candidiasis in adults and children, invasive aspergillosis in patients refractory to or intolerant of other antifungal therapy, and empirical therapy for presumed fungal infection in febrile neutropenic patients. Standard adult dosing is a single 70mg loading dose on day one, then 50mg once daily; hepatic-impairment and several drug-interaction adjustments apply. It is supplied as 50mg and 70mg vials of powder for concentrate for solution for infusion, reconstituted with water for injection before dilution into saline or lactated Ringer's for the infusion bag.
Active ingredient
Caspofungin acetate. Echinocandin antifungal (1,3-beta-D-glucan synthase inhibitor).
Forms and strengths
50 mg powder for concentrate for solution for infusion, per vial; 70 mg powder for concentrate for solution for infusion, per vial.
Indications
Caspofungin (as caspofungin acetate) is an echinocandin antifungal that inhibits fungal 1,3-beta-D-glucan synthase, indicated for invasive candidiasis, aspergillosis refractory to or intolerant of other therapy, and empirical therapy in febrile neutropenic patients. Supplied as refrigerated vials from Indian WHO-GMP facilities to regulated and semi-regulated export markets.
Administration
Intravenous. Powder for concentrate for solution for infusion.
Documentation
Batch-specific CoA, CoPP, manufacturing-site WHO-GMP certificate and stability data compiled per consignment, in the format the destination regulator expects.
Hospital pharmacies, licensed importers and tender desks across our export markets.
India is our origin. We do not sell into the Indian market.
Caspofungin buyers on our roster are mostly hospital ICU and haematology-oncology pharmacies managing invasive fungal infection in neutropenic and critically ill patients, MoH tender desks running antifungal formulary lines, NGO and humanitarian procurement teams stocking against antifungal stewardship programmes, and licensed importers and wholesalers distributing to private hospital groups. India is our origin. We do not sell into the Indian market. Caspofungin is exported only, on quote, against destination-market registration and cold-chain capability.
GCC registration routes
Supply against MoH registration held by your local licensed importer, or via the GCC central registration pathway.
UK unlicensed routes
Where no UK licence exists, the MHRA Specials and named-patient import routes cover clinically justified demand.
Tender desks
Bid-pack documentation assembled to the tender's specification, from CoPP to batch records.
Dossier support
CTD documentation from the sourcing manufacturer, compiled for your regulator's format.
What the dispensing pharmacist checks on caspofungin.
Caspofungin dosing is not one-size-fits-all: standard adult therapy is a 70mg loading dose on day one, then 50mg once daily, but moderate hepatic impairment (Child-Pugh 7-9) drops the maintenance dose to 35mg daily after the same loading dose, and severe impairment has no defined regimen. Reconstitute with water for injection, never a diluent containing glucose, since caspofungin is not stable in glucose-containing diluents, then dilute into saline or lactated Ringer's; the reconstituted concentrate holds 24 hours at or below 25°C, and the diluted infusion 48 hours refrigerated or 24 hours at room temperature. Rifampicin and other enzyme inducers push the maintenance dose to 70mg daily. Ciclosporin raises caspofungin exposure by around 35%, so review liver enzymes. Tacrolimus troughs fall by around 26% on caspofungin, so tacrolimus needs its own dose review. Unopened vials stay refrigerated at 2 to 8°C throughout transit.
The documentation pack a regulator actually asks for.
M Care sources caspofungin, originator and generic, from WHO-GMP-certified Indian manufacturing sites; some partner sites additionally hold EU-GMP status. We hold CDSCO export licensure and ISO 9001:2015 certification, and ship on cold-chain-validated lanes with temperature logging, essential for a refrigerated vial like caspofungin. M Care does not manufacture and does not hold or claim WHO-GMP or WHO Prequalification (WHO-PQ) status in its own name; caspofungin supplied through us is WHO-GMP sourced from the originating manufacturer, and we author or align CTD/eCTD dossier documentation to each destination regulator's import requirements.
Buyers new to sourcing from India usually read the licensed import route explainer first, then the product page.
CoA and MoA, per batch
Batch-specific certificate and method of analysis from the sourcing manufacturer's QC release.
CoPP, WHO-GMP, MFG licence
Certificate of pharmaceutical product and site GMP certification issued via CDSCO channels, naming the actual manufacturing site.
CTD Module 3
Chemistry, manufacturing and controls documentation available from the sourcing manufacturer for registration filings.
Pack insert, labels, artwork
Destination-language patient information and labelling to the local regulator's standard, locked before shipment.
Pharmacovigilance
A named PV contact arranged in the destination market where the registration requires one.
Adjacent lines procurement desks order alongside caspofungin.
Molecule · strength · volume · destination. One working day to a quote.
- Send us the specifics. Form and strength, pack preference, destination market and indicative volume for caspofungin.
- We route to the right line. The enquiry goes to the WHO-GMP certified manufacturing partner whose certificates fit your regulator.
- Commercial and regulatory offer. FOB or CIF price with the documentation list, named manufacturing site and current certificate validity.
- Order, produce, release, ship. QC release on the Indian side, batch documents compiled, despatch on the agreed incoterm.
- After delivery. Batch records and certificates archived and retrievable for the life of the product on your shelf.
Caspofungin supply, the specific questions.
We need caspofungin for our hospital antifungal formulary, brand or generic?
Cancidas is the originator brand, from Merck (marketed by Merck Sharp & Dohme outside the US). Generic caspofungin acetate for injection also carries its own UK-registered SmPC. M Care quotes either the originator brand or generic caspofungin acetate against your formulary specification and destination-market regulatory requirements.
Is caspofungin on WHO's Essential Medicines List for our tender specification?
Yes. Caspofungin was added to the WHO Essential Medicines List in 2021 alongside micafungin and anidulafungin, as an echinocandin therapeutic alternative for invasive candidiasis and azole-refractory aspergillosis. WHO's own guidance ranks micafungin first among the three echinocandins, citing wider country availability and stronger published data in chronic pulmonary aspergillosis and premature infants, so confirm which echinocandin your tender line specifies before we quote.
What cold chain does caspofungin need through dispatch?
Unopened caspofungin vials are stored at 2 to 8°C under refrigeration, the same as most biologicals on our roster. M Care ships on validated cold-chain lanes with temperature logging. Once your pharmacy reconstitutes the vial, the in-use storage limits for the concentrate and the diluted infusion are set out in the product label and differ between the US and EU texts, so follow the label supplied with the batch.
Does the caspofungin dose change for our hepatic-impairment patients?
Yes. No adjustment is needed for mild hepatic impairment (Child-Pugh 5-6). For moderate impairment (Child-Pugh 7-9), the SmPC recommends a 70mg loading dose on day one followed by 35mg daily. There is no clinical experience in severe hepatic impairment, so the SmPC advises caution rather than a defined dose.
Which co-medications does our pharmacy need to flag against caspofungin?
Rifampicin and other enzyme inducers raise the daily dose to 70mg after the loading dose. Ciclosporin increases caspofungin exposure by around 35%, so liver enzymes need closer monitoring. Tacrolimus trough levels fall by around 26% on caspofungin, so tacrolimus dosing needs its own adjustment. Flag all three at reconciliation.
Can M Care supply caspofungin into our market, and is India itself a market you serve?
We export caspofungin from India to GCC, African and European hospital and tender buyers; India is our origin, not a market we sell into. For your country, we align the dossier, whether CTD, eCTD or a national format, and the cold-chain shipping lane, to your regulator's import requirements before dispatch.
Who stands behind this page, and where its statements come from.
Reviewed by Dr. Rajat Bhatt, PharmD, Managing Director, M Care Exports. Last reviewed 2026-09-19.
This page is sourcing information for licensed importers, hospital procurement and tender desks. It is not medical, pharmaceutical or prescribing advice, and it is not a substitute for the approved product information of the line on your order. See our full disclaimer.
Send the specifics. You'll have a price inside one working day.
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