Colistimethate Sodium Injection Exporter and Supplier from India
You are sourcing a last-line polymyxin for MDR gram-negative infections, and continuity of supply matters as much as the price line. M Care Exports is an India-based merchant-exporter, trading since 2003, consolidating colistimethate sodium (CMS) in 1 MIU, 2 MIU and 4.5 MIU vials from WHO-GMP manufacturing lines. We ship to importers, distributors and hospital or government tender buyers across the UK, EU, GCC, Africa, Latin America and South East Asia.
Consolidating colistimethate sodium for hospital and tender procurement
Colistimethate sodium is a WHO AWaRe Reserve antibiotic: demand is concentrated in ICU, tertiary hospital and central medical store procurement rather than retail. That shapes how we source it. We do not manufacture. We buy from WHO-GMP-listed lines and stage stock against your batch schedule, so a CRE or Acinetobacter outbreak order is not left waiting on a single production window.
MIU-based, not milligram
CMS is dosed in million international units. We quote and label per MIU (1, 2, 4.5) to match how anaesthetists, intensivists and tender documents specify it, avoiding the mg-versus-MIU confusion that trips cross-border orders.
Cold-chain not required, but handling is
The lyophilised powder ships at controlled room temperature. Reconstituted solution is unstable, so we align pack sizes and vial counts to your dispensing pattern rather than pushing oversized lots.
Batch minimums set at source
Minimum order quantity follows the source manufacturer's batch-release minimum, not an arbitrary M Care figure. We confirm the exact MOQ per strength against a live enquiry.
Outbreak and tender responsiveness
Reserve-group demand spikes with resistance surveillance findings. We hold buffer stock on fast-moving strengths so a hospital antimicrobial-stewardship escalation can be filled without a full lead-time reset.
Colistimethate sodium at a glance: strengths, form and regulatory class
Active ingredient
Colistimethate sodium (colistin methanesulfonate, CMS), the inactive sulfomethylated prodrug that hydrolyses in the body to active colistin. Not interchangeable with colistin sulphate.
Strengths stocked
1 MIU, 2 MIU and 4.5 MIU vials of powder for injection or infusion, plus 1 MIU powder for nebuliser solution. Other strengths sourced to order.
Formulation and handling
Sterile lyophilised powder for reconstitution. Stored at controlled room temperature; reconstituted for IV, IM or nebulised administration and used promptly.
Regulatory class
Prescription-only injectable antibiotic. WHO AWaRe Reserve group; colistin (parenteral) is on the WHO Model List of Essential Medicines.
ATC classification
J01XB01 (polymyxins). Distinct from colistin sulphate, which is used orally or topically and is not exchangeable dose-for-dose.
Reference brands
Buyer-reference brands include Coly-Mycin M, Colomycin and Promixin internationally, and Zycolis, Coly-Monas and Xylistin from Indian lines. Supplied as requested per market.
Buyers who source colistimethate sodium through us
A Reserve antibiotic sits inside stewardship protocols and formulary restrictions, so the buyers who order it are specific. We supply the following segments in export markets, never patients and never India as a sales destination.
Hospital and ICU procurement
Tertiary and critical-care hospitals stocking a last-line agent for confirmed or suspected MDR gram-negative sepsis, where a stock-out has direct clinical consequences.
Government and institutional tenders
Central medical stores and national procurement agencies filling Reserve-group line items, who need CTD dossier and CoPP documentation to award and clear.
Importers and wholesale distributors
In-country distributors building an anti-infectives range who want a single consolidator for CMS strengths plus sibling carbapenem and glycopeptide lines.
AMR and infectious-disease programmes
Buyers serving carbapenem-resistant Enterobacterales and Acinetobacter caseloads who need reliable resupply as resistance surveillance drives demand.
Safety-critical facts buyers should carry into their market
Colistimethate sodium is dose-limited by nephrotoxicity and neurotoxicity. Renal impairment is common on treatment, so parenteral dosing is adjusted to creatinine clearance and renal function is monitored during therapy. These effects are usually reversible on dose reduction or discontinuation, but they make accurate labelling and dose documentation a genuine safety issue, not a formality.
Because CMS is dosed in million international units (MIU) and international products differ in how they express strength (MIU versus milligrams of colistimethate versus colistin base activity), the World Health Organization and product labels stress that these are not directly interchangeable. We keep MIU labelling explicit precisely to reduce that conversion risk in cross-border supply. Colistimethate sodium (IV and nebulised) must also not be confused with colistin sulphate, which is an oral or topical product and is not exchangeable dose-for-dose.
As a Reserve-group agent, use is restricted to confirmed or suspected life-threatening MDR infections where other options have failed or are unsuitable. Dosing details shown anywhere on this page are reference context for procurement teams and are not medical advice or a treatment instruction.
Written for professional buyers and importers, not as medical advice. Prescribing decisions sit with the treating clinician and the approved label in your market.
Export and registration documents we compile with you
M Care does not hold the manufacturing certifications. Those belong to the production line. What we do is assemble and forward the paperwork that lets you register, tender and clear the goods, working from the source manufacturer's records alongside our own ISO 9001:2015 trading system.
CTD dossier support
We compile the Common Technical Document alongside you for registration in your market, drawing the module data from the source manufacturer.
CoPP and free-sale
Certificate of Pharmaceutical Product and free-sale certificates arranged from the manufacturing site to support tender awards and import licensing.
Batch and quality records
Batch-specific Certificate of Analysis and manufacturing-line WHO-GMP evidence forwarded per consignment, so your QA can verify provenance.
Shipping and stability documentation
Packing list, invoice, stability data and storage-condition statements prepared to match your import-clearance and cold-chain-exempt handling requirements.
Our own credential
M Care operates an ISO 9001:2015 quality-managed trading system. We state honestly that WHO-GMP, WHO-PQ and EU-GMP are held by the manufacturer, and we supply from those lines rather than claiming them ourselves.
Molecules buyers source alongside Colistimethate Sodium.
Meropenem
Carbapenem often used alongside or ahead of colistin in MDR gram-negative regimens.
Piperacillin-Tazobactam
Broad-spectrum beta-lactam for gram-negative cover before Reserve-group escalation.
Vancomycin
Glycopeptide for resistant gram-positive cover, commonly stocked in the same ICU formulary.
How ordering works.
- Send your enquiry Tell us the strengths (1, 2 or 4.5 MIU), quantities per strength, destination market and whether the order is tender-linked. Pricing is on request against a live enquiry.
- We source and quote We confirm availability from WHO-GMP lines, the batch-release minimum order quantity at source, lead time and the documentation set your market needs.
- Documentation and dispatch On confirmation we align the CTD, CoPP, CoA and shipping paperwork, then consolidate and dispatch with batch records forwarded per consignment.
Colistimethate Sodium supply, the specific questions.
What is the difference between colistimethate sodium and colistin sulphate?
Colistimethate sodium (CMS) is the inactive prodrug given by injection or nebuliser; it hydrolyses in the body to active colistin. Colistin sulphate is a separate oral or topical product. The two are not interchangeable dose-for-dose, so buyers should confirm which product a tender or formulary actually specifies before ordering.
Which strengths of colistimethate sodium can M Care supply?
We stock 1 MIU, 2 MIU and 4.5 MIU vials of powder for injection or infusion, plus a 1 MIU powder for nebuliser solution. Other strengths can be sourced to order from the manufacturing line. Quantities per strength are confirmed against your enquiry.
Why is colistimethate dosed in MIU instead of milligrams?
Colistimethate potency is expressed in million international units (MIU) because international products differ in how they state strength: MIU, milligrams of colistimethate, or colistin base activity. These are not directly interchangeable, and the WHO and product labels flag the conversion risk. We label explicitly in MIU to keep cross-border orders unambiguous.
Does M Care hold WHO-GMP or WHO-PQ certification for this product?
No. WHO-GMP, WHO-PQ and EU-GMP are held by the manufacturer, and we supply from those manufacturing lines. M Care's own credential is ISO 9001:2015 for our trading operation. We compile the CTD dossier and CoPP alongside you from the manufacturer's records; we do not claim certifications we do not hold.
What documentation do you provide for registration and tenders?
We compile the CTD dossier, arrange the CoPP and free-sale certificate from the manufacturing site, and forward batch-specific Certificates of Analysis, WHO-GMP evidence, stability data and shipping paperwork per consignment. This is the set most import-licensing and tender-award processes require.
What is the minimum order quantity and price?
The minimum order quantity follows the source manufacturer's batch-release minimum rather than a fixed M Care figure, and it varies by strength. Pricing is on request. Send your strengths, quantities and destination and we will confirm MOQ, lead time and a quote against that specific enquiry.
Which markets do you export colistimethate sodium to?
We supply importers, distributors and hospital or government tender buyers across the UK, EU, GCC, Africa, Latin America and South East Asia. We do not sell to patients and do not supply India as a sales market. Registration requirements differ by country, which is why the documentation set is assembled per destination.
Request a colistimethate sodium quote
Send your required strengths (1, 2 or 4.5 MIU), quantities and destination market. We will confirm availability from WHO-GMP lines, the batch-release minimum order quantity, lead time and the full documentation set, with pricing on request.