Pradaxa (dabigatran etexilate) is an oral direct thrombin inhibitor capsule, taken twice daily without routine coagulation monitoring, and it is bought as originator Pradaxa or as a registered generic depending on the destination.

Yes. In the US, the FDA's 2023 first-generic approvals list includes Apotex dabigatran etexilate capsules in 75, 110 and 150 mg, with Pradaxa as the reference product. In the EU, the EMA lists Dabigatran Etexilate Accord as a generic of Pradaxa, with the marketing authorisation issued on 26 May 2023. For India, we cite no Indian regulator page here; what we can say is that Indian-made dabigatran lines (for example Dabigat and Dabigo) are on the M Care supplier roster for destinations whose registration accepts them. We do not claim any of these brands is registered in a given destination.

We do not publish a Pradaxa price, because the landed cost depends on the destination. The main drivers are originator Pradaxa or a generic, strength and pack type (bottle or blister), order quantity, the registration route in your country, shelf life required at arrival, and the Incoterms. Dabigatran needs no cold chain, which removes one cost line that biologics carry. M Care Exports quotes per destination. Send the strength, quantity and port, and we return an offer.

They are different molecules and are not interchangeable on a milligram basis. Dabigatran is a direct thrombin inhibitor with a specific reversal agent, idarucizumab, described in the Pradaxa label. Eliquis is apixaban, which M Care also quotes as a separate enquiry. The choice is made by the prescriber and the formulary, not by the supplier. What we can tell a tender desk is the supply picture for dabigatran: originator and generic capsules, room-temperature storage, and registration status per destination. Please send the formulary wording you must match.

In the EU SmPC, the 150 mg capsule is for stroke prevention in non-valvular atrial fibrillation, for treating and preventing recurrence of DVT and PE in adults, and for paediatric VTE. The 110 mg capsule covers those uses and also post-operative prevention after hip or knee replacement, and it is the reduced dose for patients aged 80 or over or on verapamil. The 75 mg capsule is listed for the post-operative prevention indication and for paediatric VTE. Labelling differs by country, so we confirm the destination label before quoting a strength.

Pradaxa is a hard capsule, not a tablet, and it must be swallowed whole. For atrial fibrillation the EU SmPC gives 150 mg twice daily, with 110 mg twice daily recommended for patients aged 80 or over or on verapamil. Renal function is estimated with the Cockcroft-Gault method, and CrCl below 30 mL/min is a contraindication in the EU. The US label differs and gives 75 mg twice daily for CrCl 15 to 30 mL/min. Dosing is the prescriber's decision, and our role is to supply to the destination's label.

Yes. M Care resells originator brands as well as generics. We can quote Pradaxa capsules and Indian-made dabigatran generics, and we say clearly which one each offer is. The route differs by market, for example the Emirates Drug Establishment (EDE) in the UAE, NAFDAC in Nigeria and the MHRA for the UK, so we confirm what your regulator accepts first. Because there is no cold chain, shipping is standard ambient freight with moisture-protected packs. M Care is a merchant-exporter, not a manufacturer.